Expanding Frontiers of Genomic Medicine Enabled by Cost-Effective Next Generation Sequencing

Collecting DNA methylation data by WGBS offers valuable insights into disease origin, predisposition, and treatment response, potentially guiding therapeutic strategies. Since the emergence of platforms such as the Illumina NovaSeqX™️, the cost of sequencing has substantially decreased, making whole genome DNA methylation profiling more cost-effective for clinical studies and diagnostic development.

In this webinar, we will discuss the challenges and opportunities for WGBS in an era of cost-effective sequencing:

• Optimizing protocols and reagents for consistent and reliable results
• Establishing community standards to ensure WGBS library quality
• Developing standardized approaches and tools for data analysis
• Integrating epigenetic and genetic information from a single WGBS run

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