Eliminating antibiotic Resistance Gene Transfer Risks in Cell & Gene Therapies

Download our whitepaper to learn about the drawbacks of traditional pUC plasmid vectors, including antibiotic resistance marker transfer, potential risk of residual antibiotic-mediated hypersensitivities, horizontal gene transfer, and how Nanoplasmid’s next-generation design mitigates these shortcomings.

In this whitepaper, you will learn about the current market trends and challenges within the cell and gene therapy (CGT) field, along with a guideline perspective of the Food and Drug Administration, European Medicines Administration, and World Health Organization relevant to clinical programs bound for commercialization.

Additionally, you will learn how Nanoplasmid’s antibiotic-free system RNA-OUT system functions and how its R6K origin of replication will aid in the following:

  • Meeting or exceeding regulator recommendations/standards
  • Demonstrating value to increasingly cautious investors 
  • Easing Regulatory Concerns 
  • Shortening project timelines 
  • Relieving manufacturing burden 

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