In this webinar, we will discuss how to use genetically engineered mouse models (GEMMs) to move your development program from discovery stage to the clinic, including how to use:

• Conditional knockout mice to screen candidates in discovery
• Humanized immune checkpoint models for proof of concept and initial in vivo screening
• CDX and PDX engraftment in immunocompromised mice to generate efficacy and safety data
• Dr. Moore and Dr. Suryani Chen will also share data from recent studies validating the use of various models.